All patients received initial periodontal therapy. All patients received a hygienic phase of treatment and were re-examined 3 months later. Both applied metronidazole concentrations were able to decrease the CFU counts by approximately one order of magnitude in a log10 scale. The GCF samples were analyzed utilizing enzyme-linked immunosorbent assays for DNA fragments and nitric oxide levels, whereas Western blotting was used for Fas/FasL analyses. However, there were no significant differences in the clinical parameters between the groups after 6 weeks and after 3 months. Graves DT, Cochran D: The contribution of interleukin-1and tumor necrosis factor to periodontal tissue destruction. Periodontal disease is characterized by periodontal bone loss. A statistically significant greater recession reduction favoring the test procedure was achieved. The ISSN of Journal of Periodontology journal is 00223492. Porphyromonas gingivalis is a major pathogen of severe adult periodontitis. Treatments that aim to reduce the accumulation of bacteria on dental surfaces are considered today as the most efficient way of treating gingivitis and the resultant destruction of periodontal tissues. BOP was significantly reduced at all sites over the duration of the study except at the Adjacent sites at three months (P<0.05). Each subject was treated with a single episode of scaling and root-planing (SRP), of approximately 90 minutes duration using ultrasonic and hand instrumentation under local anaesthetic, if indicated. For this reason, we conducted a study to test the effect of alendronate (ALN), an inhibitor of bone resorption, on alveolar bone mass. Under standardized viewing conditions, the distance from the cementoenamel junction to the interproximal alveolar crest on both the mesial and distal surfaces of each fully erupted permanent tooth present was measured. Calculus was removed in as large pieces as possible by the use of a sickle or a push scaler placed underneath the apical or facial border of the calculus and fracturing it from the tooth surface in a single stroke. For the older adults group the Il-1beta values increased significantly at day 21 and recovered at day 28. Eighty teeth in 18 patients were evaluated using a split mouth design. International Scientific Journal & Country Ranking. Several interesting observations were made after 8 years. The goal of antiretroviral therapy is the maximum suppression of viral load, restoration or preservation of immune function, improvement of quality of life and reduction of HIV-related morbidity and mortality. All samples were assayed for apoptotic markers, including Fas/FasL, DNAfragmentation, and nitric oxide. The Journal of the International Academy of Periodontology is published quarterly and includes news, comments and scientific reports on all aspects of periodontology. Treatment of Incipient peri-implant infections using topical minocycline microspheres versus topical chlorhexidine gel as an adjunct to mechanical debridement, Clinical evaluation of subgingival application of metronidazole 25%, and adjunctive therapy, The microbiological case for adjunctive therapy for periodontitis, Repeated oral hygiene instructions alone, or in combination with metronidazole dental gel with or without subgingival scaling in adult periodontitis patients: a one-year clinical study, Comparative clinical and microbiological effects of subgingival metronidazole application in adult periodontitis; 12-months results, Corticotomy-facilitated orthodontics in adults using a further modified technique, Effect of amine fluoride-containing toothpast (Meridol) on plaque and gingivitis in adults, Clinical and radiographic evaluation of bone grafting in corticotomy-facilitated orthodontics in adults, The coronally advanced flap for the treatment of multiple recession defects: a modified surgical approach for the upper anterior teeth, Cigarette smoking associated with advanced periodontal destruction in a Greek sample population of patients with periodontal disease, Dentinal hypersensitivity: Review of aetiology, differential diagnosis, prevalence, and mechanism, HIV/AIDS in Southern Africa: a major problem, Control of HIV/AIDS and AIDS-related conditions in Africa with special reference to periodontal diseases, Radiographic assessment of periodontitis in African-Americans with Down syndrome, Periodontitis associated with Chediak-Higashi syndrome in a young African American Male, Group B. This philosophy was supported by many horizontal observations in humans that confirmed the need for a certain band of attached gingiva to maintain periodontal tissue in a healthy state. A similar result was obtained in late-passage human gingival fibroblasts. Each volunteer provided four sites with probing depth > or = 5 mm. Abbreviation : IP Int J Periodontol Implantol. ISO 4(Information and documentation – Rules for the abbreviation of title words and titles of publications) is an international standard, defining a uniform system for the abbreviation of serial publication titles. The furcation areas of each molar were coated with red nail colour for artificial calculus. December 2003. Starting in January 2018, the Journal of Periodontology (JOP) and Clinical Advances in Periodontics (CAP) will be published by Wiley. The International Academy of Periodontology was established in 1985 to improve knowledge and disseminate information about periodontics worldwide to those who have an interest in the prevention and treatment of diseases of the periodontium by: Advancing international co-operation on a personal basis and in co-operation with national or international periodontal societies and research groups and appropriate health organizations; Ensuring that periodontology … The aim of the present study was to study the phenotypic and functional activities of peripheral blood mononuclear cells (PBMC) from 16 patients with generalised aggressive periodontitis (G-AP), 13 patients with chronic periodontitis (CP) and 20 periodontally healthy subjects (H). All subjects showed sites with bone loss > or = 3 mm. There was a statistically significant difference between the two groups regarding the treatment duration: 17.5 +/- 2.8 weeks in the CFO group and 49 +/- 12.3 weeks in the conventional orthodontic therapy group. International Academy of Periodontology Journal of the International Academy of Periodontology Boston, Mass. Each of the 15 adult subjects included in the study had to present with at least two pairs of adjacent 6-9 mm pockets each pair located on adjacent teeth in an interproximal space, on opposite sides of the mouth. Treatment duration for patients in both groups ranged from 14-20 weeks. The results of the current study suggest that corticotomy-facilitated orthodontic tooth movement significantly reduces the total time of treatment. All periapical radiographs were taken with a long cone paralleling technique under normal clinical practice conditions. An International Standard Serial Number (ISSN) is a unique code of 8 digits. MD Scanner. Our objectives were to investigate the effects of alcohol exposure on neutrophil function and the associated consequential effects on the periodontium in a group of African American (AA) males with documented history of alcohol use without medical complications. Areas of skin depigmentation were noted. All patients received prophylaxis at baseline, and at 6, 12, and 18 months. Semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) using total RNA was used to determine relative expression of MMP-13 compared to glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a constitutively expressed housekeeping gene. The Journal of the International Academy of Periodontology is published quarterly and includes news, comments and scientific reports on all aspects of periodontology. Only Open Access Journals Only SciELO Journals Only WoS Journals The objective of this study was to investigate the effect of alendronate sodium, systemically induced in the treatment of patients with periodontitis. September 2020. A paired samples t-test was used to compare the radiographic bone levels of DS and MC subjects. After instrumentation the percentage of the furcation area with residual artificial calculus was assessed using a computerised imaging system. The incorporation of bone graft material significantly increased the alveolar bone density in adult patients. Clinical examinations were carried out before treatment and 90 days after treatment. This was the only difference in the cytokines values between older and young adults. The purpose of this cross-sectional study was to investigate the periodontal status and aspartate aminotransferase and lactate dehydrogenase enzyme activities in gingival crevicular fluid (GCF) of type 2 diabetic and/or obese chronic periodontitis patients. A significant reduction in the percentage of bleeding sites during the six-month study period was found in the AmF/SnF2 group, but not in the control group. Thyroid hormones play an important role in the regulation of physiologic processes. Group I demonstrated a net decrease in bone density of 21.8%, while Group II demonstrated a net decrease of 37.2%. Tetracycline fibres were applied in 5 pockets located in the same half mouth. Alveolar bone width was clinically assessed immediately after tooth extraction and 6 months after bone grafting, at the time of implant placement. Pages: i, 1-352. Dentine exposure results from a combination of two or more aetiological factors that lead to loss of enamel and/or loss of cementum. Mouse dermal and late-passage human gingival fibroblasts in vitro are likely to be altered in phenotype into IL-8-producing cells along with the production of IL-1beta. Dentinal hypersensitivity is a painful response to a non-noxious stimulus applied to exposed dentine in the oral environment. A split-mouth experimental design was used. It led to a decrease in hs-CRP. The primary efficacy endpoint was the change in alveolar bone loss (ABL). The mean gains in probing attachment level were 2.2 mm, 1.9 mm, 2.7 mm and 1.6 mm, respectively. Periodontal treatment led to a significant improvement in periodontal indices; only five patients required periodontal surgery. Review articles, reports of scientific meetings in periodontology and other short communications are also published in the journal. Sutures were removed ten days after surgery. Clinical examination revealed that the upper right central incisor had a recession of 7 mm. Necrotizing ulcerative gingivitis may progress in some cases to ulcerative necrotizing stomatitis, necrotizing ulcerative periodontitis, and, finally, to noma. Periodontal therapies, including dental implant placement, appear to be safe with no increase in treatment failure, so long as the status of the thyroid gland is controlled. The Journal Impact 2019-2020 of Journal of the International Academy of Periodontology is 2.750, which is just updated in 2020.Compared with historical Journal Impact data, the Metric 2019 of Journal of the International Academy of Periodontology grew by 186.46 %.The Journal Impact Quartile of Journal of the International Academy of Periodontology is Q3. Highly active antiretroviral therapy (HAART) has had a major impact on HIV-related deaths and illnesses. Comprehensive dental, medical and laboratory evaluations were performed. The LAP diseased sites had attachment loss ranging from 5-12 mm. P. gingivalis is more common in Hispanics, Asians and Blacks than in Caucasians. Each patient had one or more implants with probing depth > or = 4 mm combined with bleeding and/or exudate on probing and presence of putative pathogenic bacteria. Ninety-eight women and sixty-two men, age range 15-70 years, were interviewed and examined. In addition, the incidence of apical root resorption and periodontal problems associated with orthodontic tooth movement were reduced. Microbial studies among new Colombian NUG, NUP and noma patients are necessary, using bacterial culturing and identification methods and molecular techniques such as PCR for viruses and bacteria, in order to establish the exact nature of these lesions. Reactor report. Subgingival plaque samples were taken for microbiological analysis using the 'checkerboard' DNA-DNA hybridisation technique at baseline, immediately after treatment and at 2 and 6 months. Ten suitable patients were included in this randomized single-blind clinical study with an intra-individual design. Ten patients, 24-39 years old referred for treatment to the Department of Preventive Dentistry, Periodontology and Implant Biology, Aristotle University of Thessaloniki took part in the study. Advanced periodontitis is an important symptom of CHS and may be the first step in the diagnosis of the condition. The four treatment groups were: (I) One session of one hour of scaling and root planning, (II) metronidazole 25% dental gel (ELYZOL DENTAL GEL) applied on day 0 and day 7, (III) scaling adjunctive to metronidazole 25%, and (IV) No treatment. Journal of Periodontology Established in 1930 as the official publication of the AAP, the Journal of Periodontology (JOP) publishes original papers of the highest scientific quality to support practice, education, and research in the dental specialty of periodontics. At the 12-month examination, the mean reductions in probing pocket depth were 2.6 mm after OHI alone, 2.8 mm after OHI and metronidazole gel, 3.3 mm after OHI and subgingival scaling and 2.6 mm after oral OHI and subgingival scaling plus metronidazole gel. The aim of the present study was to investigate the long-term effect of amine fluoride/stannous fluoride (AmF/SnF2) toothpaste on plaque levels and gingivitis in adults, as an additional measure to standard oral hygiene. The gingival tissues were swollen and bled easily. The results of this study suggest that smoking appears to be a major environmental factor associated with accelerated periodontal destruction in an adult urban Greek population with regular oral hygiene habits. Tooth extractions are recommended to eliminate the periodontal problems and reduce the risk of fatal bacterial infections. They may be cancellous bone, cortical bone, or combinations of these. Ip International Journal Of Periodontology And Implantology specialize in publication of digital advertisement to help clients inform and attract new customers easily and efficiently. These results suggest that the use of the P-15 synthetic cell-binding peptide combined with ABM yields better clinical results than DEBR. A complete clinical examination and measurements of HbA1c and hs-CRP were evaluated. Subgingival plaque samples were taken at every examination from one selected site in each quadrant. Histomorphometric analyses of sockets grafted with SCPC for 6 months revealed 46.8% +/- 14% new vital bone and 2.5% +/- 1.5% graft material remnants. The teeth in the fourth group (G4) were scaled, root planed, and then conditioned with the EDTA gel preparation for 2 minutes before immediate extraction. Samples were prepared for transmission electron microscopic (TEM) observation after immunogold staining with polyclonal antibodies for the presence of Actinobacillus actinomycetemcomitans (A. International Journal of Implant Dentistry is an international online-only open access journal publishing high-quality peer-reviewed articles related to the field of implant dentistry.. Generously provided by Érica Dorigatti de Avila from the Department of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista - UNESP, Araraquara, São Paulo, Brazil. Publications. All patients had at least one tooth in each quadrant with probing pocket depth of > or = 5mm. Blood levels of gamma-glutamyl transpeptidase (GGTP) were determined and used as a measure of alcohol consumption. Severe periodontitis with tooth loss as a modifiable risk factor for the development of Alzheimer, vascular, and mixed dementia: National Health Insurance Service-National Health Screening Retrospective Cohort 2002–2015 Smokers accounted for 62% of patients, and 71% of the patients had severe periodontal disease. Mean pocket depth reduction from baseline in the 1710 patients was 1.82 mm (p < 0.0001) and for the 1095 patients at 6 months it was 1.94 mm (p < 0.0001). The results of this study suggest that SCPC graft material reduces the amount of change in alveolar ridge dimensions after tooth extraction and facilitates the regeneration of new vital bone. Periodontol.”. All patients completed the trial. The clinical outcomes were measured at baseline, 6 weeks and 3 months after treatment. This report presents the clinical results three months after application of minocycline microspheres as an adjunct to mechanical treatment of incipient peri-implant infections compared to adjunctive treatment employing 1% chlorhexidine gel application. The aim of the study was to evaluate the clinical efficacy of a modification of the flap-design of the coronally advanced flap for the treatment of multiple gingival recessions affecting the anterior teeth in patients with aesthetic demands. Almost all the patients came from low socioeconomic groups and presented with predisposing and/or contributing factors, such as acute herpetic gingivostomatitis, measles, and leukemia (including acute lymphoblastic and chronic lymphoid leukemia). The majority of proliferating cell nuclear antigen-immunopositive cells was found in the basal layer. The second group (G2) served as a diseased treated control in which sample teeth were only scaled and root planed prior to immediate extraction. The amount of root coverage obtained after a graft procedure may be improved after the early phase of healing by a coronal displacement of the gingival attachment. Noma can be prevented by vaccinating children against infectious diseases, by controlling malnutrition and by improving their oral hygiene. A total of 335 patients with periodontal disease (men = 162, women = 173), aged 30 to 79, were randomized to either placebo or ALN 70 mg once weekly. Alendronate sodium had no effect on the clinical parameters and could play an important role as an adjunct to conventional periodontal therapy in management of periodontal diseases. Periodontics. Treatment includes professional plaque control, debridement to remove necrotic debris, irrigation with antiseptic mouthwashes (chlorhexidine, povidone iodine) and the use of systemic antibiotics in selected cases. Full-mouth series of intraoral periapical (PA) radiographs of 25 AA DS patients (age range 18-64 years, 36% males) were randomly selected from a special care dental center for the handicapped. There was a trend for greater improvement in all clinical parameters at the MPTS sites compared with the Adjacent and Remote sites except for plaque scores. International Journal of Periodontics & Restorative Dentistry Editor in Chief: Myron Nevins, DDS, Marc L. Nevins, DMD, MMSc Impact Factor (ISI): 1.513 (2019) An international reputation for high-quality editorial content and unparalleled color illustrations has created a loyal following for this elegantly produced journal. Six systemically and periodontally healthy subjects with multiple recession-type defects affecting the upper incisors and canines (recession depth < or = 2 mm) were enrolled in the study. Group I, included twelve patients who received one tablet of fosamax (alendronate sodium, MSD) every morning for six months. Smears from plaque samples were silver-stained and differential counting was performed under light microscopy at 1000X magnification. These results suggest that fibroblasts remain insensitive to IL-1beta and TNF-alpha so as to induce the IL-8 gene expression in non-inflammatory mice skin. The clinical re-evaluation was made one year after the surgery. according to the same "cyclical" regimen. The purpose of this study was to compare an ultrasonic furcation tip with an ultrasonic conventional tip and a hand scaler on accessibility to furcation areas of mandibular first and second molars. Recent studies have demonstrated the effectiveness of locally delivered antibiotics adjunctive with scaling and root planing (SRP) in patients with chronic periodontitis. Subgingival microbiological culture showed the presence of Porphyromonas gingvalis, Prevotella intermedia and Tannerella forsythia. The Journal of International Academy of Periodontology. Periodontitis is a problem in AA patients. Both groups showed a significant reduction in periodontal pocket depth (PPD) and gain in clinical attachment level (CAL) after treatment. The results of controlled randomized clinical studies, Comparative clinical study of a subepithelial connective tissue graft and acellular dermal matrix graft for the treatment of gingival recessions, Root coverage in a class IV recession defect achieved by creeping attachment: a case report, Clinical effects of removable acrylic appliance design on gingival tissues: a short-term study, Update on Actinobacillus Actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease, Identification of Actinobacillus actinomycetemcomitans, Treponema denticola and Porphyromonas gingivalis within human dental calculus: a pilot investigation. In conclusion, the clinical and microbiological data of the present study suggest that the adjunctive use of TCF improves the clinical response of scaling and root planing in aggressive periodontitis patients. journal of periodontology. It is suggested that topical Elyzol treatment may improve periodontal health as well as subgingival scaling and root planning therapy, and adjunctive treatment could obtain an additional therapeutic effect. The defect was classified as class IV according to Miller's classification of marginal tissue recession. The European Federation of Periodontology is a federation of 29 member societies for dentists specialising in Periodontics across Europe. No differences were found between LDD- and placebo-treated groups regarding any of the clinical parameters and gingival crevicular fluid enzyme activities. The first one compared the use of the acellular dermal matrix with the subepithelial connective tissue graft and showed 1.83 and 2.10 mm of recession reduction, respectively. Issue Volume 8, Issue 1. No cases of osteonecrosis of the jaw were observed. This was followed by a single application of 1 mg of minocycline in the form of Minocycline Periodontal Therapeutic System (MPTS) into one of the four sites selected at random by another clinician, who also randomly selected one of the two sites on the opposite side of the mouth to be designated the Remote site. Frequency : Quarterly. starchflour) b.i.d. Both groups I and II had statistically significantly greater improvement (P < 0.05) in probing pocket depth than control group. Pages: i, 1-352. Because no statistically significant differences between the groups were observed, it was concluded that the allograft can be used as a substitute for the autograft. Four months after grafting, the amount of root coverage obtained was 4 mm. The International Academy of Periodontology was established in 1985 to improve knowledge and disseminate information about periodontics worldwide to those who have an interest in the prevention and treatment of diseases of the periodontium by: Advancing international co-operation on a personal basis and in co-operation with national or international periodontal … While synthesis of effective vaccines is still at an early stage, containment of the pandemic requires a holistic response through an integrated approach of prevention, treatment and improvement in living conditions. However, none of the differences between the study groups were statistically significant (P > 0.05). All individuals were clinically examined and answered a detailed questionnaire. When the horizontal pocket depth was more than 2mm, the ultrasonic conventional tip and the hand scaler showed less removal of artificial calculus than the ultrasonic furcation tip (P < 0.01). No significant differences in age, gingival index, plaque index, aspartate aminotransferase and lactate dehydrogenase enzyme activities were observed, but probing depths were significantly higher in the DM groups than in the control group. Clinical periodontal parameters and standardized periapical radiographs were recorded at baseline, post-orthodontic treatment (debracketing time) and six months post-operatively. However no statistically significant differences in pocket depths were found between treatment groups over the six months of the study. The percentage of root coverage was 82.5% and 62.3% for test and control groups. The aim of this study was to assess the effects on the gingiva when an experimental palatal acrylic removable appliance, was worn for 3 weeks. Amoxicillin 3 μg/mL revealed a reduction of 2.4 log 10 CFU, whereas 50% of the samples did not grow on the plates supplemented with 8 μg/mL of amoxicillin. The clinical attachment level and the crevicular IL-1beta level were significantly lower in group 1 (0.8 W) than in the control (p<0.05). The Standard Abbreviation (ISO4) of Journal of Periodontologyis “J. In the control group, a connective tissue graft in combination with a coronally positioned flap was used; in the test group, an acellular dermal matrix allograft was used as a substitute for palatal donor tissue. A clinical pilot study over six months, of sites adjacent to and remote from the antibiotic application. However, CMT-8 inhibited MMP-13 expression from IL-1b and PTH stimulated cells while having little effect on TNF-alpha stimulated MMP-13 expression. December 2003. International Journal of Periodontics & Restorative Dentistry is published by Quintessence Publishing Co, Inc, 4350 Chandler Drive, Hanover Park, IL, 60133, USA. Further controlled studies are needed to explore the relationship between thyroid hormone imbalance and periodontal status. The purpose of this investigation was to study the surface topography of periodontally-affected human roots following EDTA gel application at different time periods with and without scaling and root planing. Alendronate sodium is a potent inhibitor of bone resorption which has been effectively used to control osteolysis, and to treat Paget's disease and osteoporosis. Efficiency of the ultrasonic furcation tip was fairly satisfactory for the horizontal pocket up to the ridge of the furcation roof. Results showed that when the horizontal pocket depth was less than 2mm, all three instruments showed good accessibility. The aim of this presentation was to discuss the effectiveness of the acellular dermal matrix in root coverage therapy and in alveolar ridge augmentation, based on three controlled randomized clinical trials conducted by our research team (Novaes Jr et al., 2001; Barros et al., 2005; Luczyszyn et al., 2005). A total of 25 recessions (mean recession depth 2.84 +/- 1.0 mm) were treated. It is arrested by mechanical lesion debridement, improving oral hygiene and antibiotic therapy. Immunoreactivity for involucrin was observed in all layers except for the basal layer. Journal of Periodontology 2003; 74:391-401. The aim of the present study was to evaluate the clinical and microbiological effects of subgingival application of 25% metronidazole dental gel as an adjunct to scaling and root planing (SRP) in the treatment of adult periodontitis. To our knowledge, this is the first report of apoptotic biomarkers associated with patients diagnosed with LAP. The study population was divided into four groups according to body mass index and type 2 DM status: 1) type 2 DM obese patients, n = 8; 2) type 2 DM patients, n = 12; 3) obese patients, n = 8; 4) systemically healthy control group, n = 11. The sociodemographic characteristics and periodontal findings were recorded and statistically analyzed. A reciprocal relationship between diabetes mellitus and chronic periodontitis has been described, whereby chronic periodontal infection could affect diabetic metabolic control. A single, masked examiner performed clinical assessments. The duration from disease onset to treatment of thyroid disorders may be critical, since uncontrolled thyroid disease may result in destruction of the periodontium. In this subject cohort, 31.3% had never smoked, 15.7% had quit smoking, and 53% were currently smokers (heavy, moderate, or occasional). Plaque index, gingival index, and probing depth were recorded on days 0, 7, and 21, and at day 42. Type 2 diabetes mellitus and obesity are the most common nutritional disorders in developed and developing countries. In situ hybridisation revealed that fibroblasts did not express IL-8 mRNA whereas keratinocytes and endothelial cells did in IL-1beta- or TNF-alpha-injected mice skin. 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